NCT05919160
A High-density Microelectrode for Human Neuronal Recordings
Enrolling by Invitation
NAAges 18+InterventionalDevice feasibilityCedars-Sinai Medical CenterInvestigator-initiated
~10 participants
Updated 2025-12-30 on ClinicalTrials.gov
What's tested:DBC (Diagnostic Biochips) Deep Array microelectrode; Intan Electrophysiology recording system; Matlab response recording to behavioral task
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Neuronal Activity
Measured over One week after recording in OR completed
+1 more outcome measured
Conditions
Where it's being run
1 sites across 1 statesCalifornia1
Study leadership
- Adam Mamelak, MD · PRINCIPAL_INVESTIGATOR · Cedars-Sinai Medical Center
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Any patient undergoing implantation of a Deep Brain Stimulating (DBS) electrode in the Subthalamic nucleus (STN) for the treatment of Parkinson's disease, in whom microelectrode recording is being performed to improve localization of the STN.
Age \> 18 years of age
Able to give independent informed consent
Exclusion
Microelectrode recording is not indicated
Previous implantation of DBS electrodes in this site
Known allergic reaction to stainless steel or polyimide
What this trial measures
- Neuronal ActivityOne week after recording in OR completed
Single Neuron firing rate (spikes) measured in spikes per second - total number of isolated neurons, amplitude (in uV of spikes) - by Intan Neurophysiology Recording System
- Breakage of ElectrodeOne week after recording in OR completed
Extent of fracture of electrode tip measured in micrometers by a light microscope