Aspirin for Postpartum Preeclampsia
This study is looking at whether low-dose aspirin (Aspirin 81Mg Ec Tab) can help women recover from severe preeclampsia (a high blood pressure condition during pregnancy) after they have given birth. Researchers believe that taking aspirin for the first week after delivery might help by lowering levels of a protein called soluble fms-like tyrosine kinase (sFlt-1), which is thought to contribute to preeclampsia. The goal is to see if aspirin can help blood pressure return to normal more quickly. To join, you must be a woman aged 18 or older who has been diagnosed with severe preeclampsia during your delivery hospital stay, according to ACOG (American College of Obstetricians and Gynecologists) guidelines. You also need to receive your pre- and postnatal care from specific clinics. The study aims to enroll 86 participants, but its current status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 86 women.
- What's involved
- Participants randomized to receive aspirin will take one 81 mg tablet by mouth nightly at 8:00 PM for one week, starting within 24 hours of delivery. Your sFlt-1 levels will be measured at 1 week postpartum.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for at least 1 week postpartum to measure sFlt-1 levels.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Aspirin for Postpartum Patients With Preeclampsia
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Megan C Oakes, MD MSCI · PRINCIPAL_INVESTIGATOR · Miller Children's and Women's Hospital, Long Beach/ MemorialCare Medical Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Reduction in sFlt-11 week postpartum
This outcome will determine the absolute change in sFlt-1, an anti-angiogenic protein implicated in the pathophysiology of preeclampsia.