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Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial

This study is for older adults (age 60 and up) who have heart disease and are eligible for cardiac rehabilitation. This includes people who have had a heart attack, heart failure, angioplasty with stent, bypass surgery, or heart valve surgery in the past six months. The goal is to compare two ways of guiding exercise during cardiac rehabilitation. One group will follow standard exercise plans (RPE), while the other will have a personalized exercise plan based on a graded exercise test to find their target heart rate range (GXT+THHR). Researchers want to see if one method leads to better fitness. This study builds on earlier research and will involve 320 participants across two medical centers.

Study design
This is a randomized study comparing two groups: one receiving standard care (RPE) and another receiving personalized care (GXT+THHR). It plans to include 320 participants.
What's involved
You would complete a baseline assessment, including a 6-minute walk test and other physical performance tests. You would also wear an accelerometer for 7 days to track your activity.
Compensation
Not stated in the trial record.
Follow-up
Your functional fitness will be measured from the start of the study until your final cardiac rehabilitation session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05925634

Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial

Active, Not Recruiting
NAAges 60–99InterventionalTreatment
Baystate Medical Center
~320 participants
Updated 2026-08-04 on ClinicalTrials.gov
What's tested:RPE (usual care)GXT+THHR (intervention)

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Functional Fitness
Measured over Baseline to final CR session

Conditions

Myocardial Infarction
Coronary Artery Bypass
Percutaneous Coronary Intervention
Heart Failure
Cardiac Valve Surgery

Explore related trials

Aortic Valve SurgeryCoronary Artery Bypass SurgeryHeart FailureMyocardial InfarctionPercutaneous Coronary Intervention

Where it's being run

2 sites across 2 states
Massachusetts1
Michigan1

Study leadership

  • Quinn R Pack, MD · PRINCIPAL_INVESTIGATOR · Baystate Medical Center

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients who are eligible for cardiac rehabilitation by having had a cardiac event such as a myocardial infarction (heart attack), heart failure, percutaneous coronary intervention or angioplasty with stent, coronary artery bypass graft, or heart valve surgery in the past 6 months.
Lives in, or plans to reside in, the Springfield, MA, or greater Detroit, MI, area for the next year.
Recruited from a Phase 2 Cardiac Rehabilitation Center at either Baystate Medical Center or Henry Ford Health System.
Age ≥ 60 years
Agrees to attend at least 18 sessions of cardiac rehabilitation after randomization
Agrees to attend cardiac rehabilitation at least twice a week

Exclusion

Permanent atrial fibrillation
Heart transplant
Left-ventricular assist devices
Stable angina
High-risk un-revascularized coronary artery disease
Symptomatic peripheral artery disease
Aortic and/or mitral stenosis
Any condition where exercise testing or training might be unsafe or limited

What this trial measures

  • Change in Functional FitnessBaseline to final CR session

    Change in functional fitness as measured by 6 minute walk from baseline to cardiac rehabilitation (CR) completion.