This study, called MICA, is looking at how breathing exercises might help children aged 6 to 17 with moderate to severe asthma, especially those who are also obese. Researchers want to understand if problems with breathing muscles or small airways contribute to asthma symptoms in these children. Participants will use a device called PrO2™ for inspiratory training (breathing exercises) at different intensity levels (low, high, or a very low "sham" level) for 8 weeks. The study will measure changes in breathing muscle function and small airway function to see if the training helps. The goal is to see if this training can improve asthma control.

Study design

This is a randomized, sham-controlled study involving 76 participants, comparing three different levels of inspiratory training.

What's involved

You would use the PrO2™ device for inspiratory training (150 inspirations three times weekly) for 8 weeks, with baseline and 8-week visits.

Compensation

Not stated in the trial record.

Follow-up

The primary outcomes are measured at 10 weeks after the start of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.