This study is looking for Veterans aged 18 to 75 with schizophrenia spectrum disorders (like schizophrenia, schizoaffective disorder, or delusional disorder) or those in good general mental and physical health. The goal is to develop new brain-based tools to help identify which Veterans with chronic psychosis might benefit most from therapies that improve thinking skills. Researchers will use non-invasive electroencephalography (EEG, a test that measures brain waves) to find specific brain markers called "Aperiodic Spectral Biomarkers." The study will assess the reliability of these biomarkers over about 7 days. This is an observational study, meaning you won't receive a new treatment, but researchers will gather information. The study plans to enroll 80 Veterans, but its current recruitment status is unclear.

Study design

This is an observational study planning to enroll 80 Veterans, divided into two phases. It involves comparing Veterans with schizophrenia spectrum disorders to those in good general health.

What's involved

You would undergo comprehensive neurophysiological, clinical, cognitive, and functional assessments. This includes systematic neurophysiologic testing on two separate visits, 1-2 weeks apart, and potentially 1 hour of cognitive training.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint measures the reliability of biomarkers at approximately 7 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.