TRAIN AD 2.0 for Reducing Antimicrobial Use in Nursing Home Residents with Dementia

This study, called TRAIN AD 2.0, is looking for ways to reduce the use of antibiotics in nursing home residents who have moderate to advanced dementia. It tests a special training program for caregivers and family members that aims to improve how they manage suspected infections like urinary tract infections (UTIs) and lower respiratory tract infections (LRIs). The goal is to see if this training can lead to less antibiotic use and fewer difficult medical procedures for these residents. You might be able to join if you are 60 to 106 years old, have any type of dementia, and have been in a nursing home for more than 90 days. The study will measure antibiotic use after 12 months to see if the training was successful. The current status of this study is unclear.

Study design
This study is a cluster randomized trial involving 750 participants across 50 nursing homes. Some nursing homes will receive the TRAIN AD 2.0 training, while others will continue with their usual care.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months to measure antibiotic use.

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NCT05950607

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Recruiting
NAAges 60+InterventionalHealth services
Hebrew SeniorLife
~750 participants
Updated 2026-01-06 on ClinicalTrials.gov
What's tested:TRAIN AD 2.0

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Antimicrobial use in residents with moderate to advanced dementia
Measured over 12 months
Dementia
Alzheimer Disease
Infections
1 sites across 1 states
Massachusetts1
  • Susan Mitchell, MD, MPH · PRINCIPAL_INVESTIGATOR · Hebrew SeniorLife

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  • Antimicrobial use in residents with moderate to advanced dementia12 months

    Number of antimicrobial courses/person-year among residents with moderate to advanced dementia.