NCT05950724

RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung Transplant

Enrolling by Invitation
EARLY_PHASE1Ages 18+InterventionalPrevention
Northwestern University
~20 participants
Updated 2026-02-10 on ClinicalTrials.gov
What's tested:Etanercept Injection [Enbrel]

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Occurrence of kidney dysfunction immediately after lung transplant
Measured over Immediately after lung transplant
+2 more outcomes measured
Lung Transplant; Complications
1 sites across 1 states
Illinois1
  • Chitaru Kurihara, MD · PRINCIPAL_INVESTIGATOR · Northwestern University

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Planning to undergo transplantation of the lung at Northwestern Memorial Hospital.
Willing and able to read, understand, and be capable of giving informed consent.

Exclusion

Previous or current use of TNFa antibody.
Positive virtual or retrospective crossmatch or highly sensitized (pRA \> 30%) recipients.
Any condition that, in the opinion of the attending physician, would place the patient at undue risk by participating.
  • Occurrence of kidney dysfunction immediately after lung transplantImmediately after lung transplant

    Measured by serum creatinine blood tests

  • Occurrence of kidney dysfunction post-operatively within 1 week after lung transplantWithin 1-7 days after lung transplant

    Measured by serum creatinine blood tests

  • Occurrence of kidney dysfunction post-operatively within 1 month after lung transplantUp to 30 days after lung transplant

    Measured by serum creatinine blood tests