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Observational Study on Heart Function During Anesthesia

This study aims to understand how your heart function (how well your heart pumps blood) and blood flow change when you receive general anesthesia for surgery. Researchers are especially interested in these changes if you experience low blood pressure (hypotension) after anesthesia. You might be able to join if you are an adult (18 or older) needing general anesthesia and intubation for surgery, with at least 20 minutes of preparation time before the incision, and a baseline blood pressure above 70mmHg. The study will look at the percentage of patients who have low blood pressure within 20 minutes after anesthesia starts. The current recruitment status is unclear.

Study design
This is an observational study planning to include 250 participants. It is not testing a new treatment but rather observing changes during standard medical procedures.
What's involved
You would have echocardiography (an ultrasound of your heart) and blood pressure measurements taken before, immediately after anesthesia starts, and after intubation for about 20 minutes.
Compensation
Not stated in the trial record.
Follow-up
The primary measurement for the study is taken up to 20 minutes after anesthesia induction.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05954832

A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

Recruiting
Not specifiedAges 18+Observational
Memorial Sloan Kettering Cancer Center
~250 participants
Updated 2026-08-10 on ClinicalTrials.gov
What's tested:Echocardiography

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The proportion of patients with post-induction hypotension (PIH)
Measured over up to 20-mins after anesthesia induction.

Conditions

Anesthesia

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Anesthesia Procedure

Where it's being run

1 sites across 1 states
New York1

Study leadership

  • Anahita Dabo-Trubelja, MD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

Who to contact

Anahita Dabo-Trubelja, MD
[email protected]
212-639-3279
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adult patients ≥ 18 years of age requiring general anesthesia for surgery
Intubation required for anesthetic management / surgery
Anticipated prep time before incision of 20 minutes
Baseline MAP \>70mmHg

Exclusion

History of coronary artery disease
History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)
History of peripheral artery occlusive disease
Beta-blocker use
Anti-hypertensive medication use
Patients with epidural, spinal, paravertebral, serratus blocks preoperatively
Patients requiring rapid sequence induction (where intubation occurs concurrently with induction)
Emergency surgery

What this trial measures

  • The proportion of patients with post-induction hypotension (PIH)up to 20-mins after anesthesia induction.

    summarize the distributions of the echocardiography parameter values (pre-load LVEDd(cm), after-load LVEDs(cm), other measures \[e.g., contractility (EF %) and structural abnormalities\]) across each timepoint among patients with and without PIH