Data Collection for Von Hippel Lindau Disease

This study is collecting information from people with Von Hippel Lindau (vHL) disease. The goal is to learn more about how vHL disease develops, what treatments (like surgeries or therapies) people receive, and how it affects their quality of life. Researchers will gather data on how lesions (growths) appear, past surgeries, and the use of a drug called belzutifan. They also want to see if there's a link between your specific vHL gene change and how the disease progresses or how you respond to belzutifan. You can join if you are 18 or older, have a confirmed diagnosis of vHL disease, and are willing to sign a consent form. The study will track how your disease progresses over an average of one year.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It aims to enroll 125 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed through study completion, which is an average of one year, to track progression-free survival (PFS).

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NCT05955014

Data Collection Protocol for Patients With Von Hippel Lindau Disease

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~125 participants
Updated 2026-06-26 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Progression-free survival (PFS)
Measured over through study completion; an average of 1 year
Von Hippel Lindau Disease

NCT05955014

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • M D Anderson Cancer Center

    Houston, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

Presence of genetic confirmation or clinical criteria consistent with vHL disease.
Ability to understand and the willingness to sign a written informed consent document.
  • Progression-free survival (PFS)through study completion; an average of 1 year