High-Intensity Exercise for Vascular and Cognitive Health in Adults with HIV
This study is looking at how different types of exercise might help adults aged 50 and older living with HIV who are experiencing some memory or thinking problems. Researchers want to see if 16 weeks of High-Intensity Interval Training (HIIT) or Continuous Moderate Exercise can improve blood vessel health (vascular function) and thinking abilities (cognitive function). The study will compare these two exercise programs to see which one works better. They also want to understand what makes it easier or harder for people to stick with exercise. To join, you must be 50 or older, have a sedentary lifestyle, have some neurocognitive impairment, and be on stable HIV medication. The study aims to enroll 60 participants in Birmingham, Alabama, but its current recruitment status is unclear.
- Study design
- This is a single-site, randomized study comparing two exercise programs. It plans to enroll 60 participants.
- What's involved
- You would participate in a 16-week exercise program, with data collected at the start, after 16 weeks, and three months after the program ends.
- Compensation
- Not stated in the trial record.
- Follow-up
- You will have a follow-up visit three months after the exercise intervention is completed.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
At a glance
Conditions
NCT05965518
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Alabama at Birmingham
Birmingham, Alabamastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Raymond Jones, Ph.D. · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham
Who to contact
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Inclusion
Exclusion
What this trial measures
- Change in vascular functionBaseline, Up to 16 weeks, 3-months Post-Intervention
Arterial stiffness is a continuous measure of cardiovascular disease risk.
- Change in cognitive functionBaseline, Up to 16 weeks, 3-months Post-Intervention
Cognitive function will be measured using BRACE+, a neuropsychological battery