NCT05967585

Implementing an Adolescent and Young Adult (AYA) mHealth Vaping Cessation Program Into Oncology Clinics

Active, Not Recruiting
NAAges 13–24Interventional
St. Jude Children's Research Hospital
~539 participants
Updated 2026-06-17 on ClinicalTrials.gov
What's tested:Behavioral: Quitting Program (TIQ)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
E-cigarette use
Measured over Baseline, 1-week post TIQ completion
+15 more outcomes measured
Vaping
Vaping Cessation
1 sites across 1 states
Tennessee1
  • Rachel Webster, PhD · PRINCIPAL_INVESTIGATOR · St. Jude Children's Research Hospital

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Research participant is 13 to 24 years old at enrollment
Research participant is followed by St. Jude Children's Research Hospital (SJCRH)
Research participant has a diagnosis of malignancy or a CNS neoplasm
Research participant has been identified by the Transition Oncology Program (TOP) as a patient transitioning off active cancer therapy and/or followed by After Completion of Therapy (ACT) Clinic, and/or participating in the St. Jude Lifetime Cohort Study (SJLIFE)
Research participant is in remission and at least 3 months from having completed cancer-directed therapy
Participant can speak and read English
Engaged in the healthcare of survivors seen through TOP, ACT, or SJLIFE

Exclusion

Significant psychiatric or neurologic disorders that would impair compliance with study protocol as indicated by the medical chart
  • E-cigarette useBaseline, 1-week post TIQ completion

    Current e-cigarette use (yes/no). This question assesses whether or not a participant is currently using e-cigarettes.

  • E-cigarette frequencyBaseline; 1-week post TIQ program completion]

    E-cigarette frequency of use assesses how often a participant is using e-cigarettes (daily to less than monthly)

  • Motivation and contemplation to quitBaseline; 1-week post TIQ program completion

    These questions assess how motivated someone is to quit e-cigarettes (not all motivated to very motivated)

  • Prior history of e-cigarette quittingPhase 2, 4-weeks post implementation

    This assessment explores if a participant has tried to quit vaping and how many quit attempts were made. (yes/no; if yes, how many quit attempts)

  • Patient Preferences for E-Cigarette Use Assessment and Referral ProcessesBaseline; 1-week post TIQ program completion]

    Semi-structured interviews will assess preferences for assessment of e-cigarette use within oncology clinic settings and referral for cessation programs.

  • Healthcare Provider Perspectives of Program Implementation PotentialBaseline; 1-week post TIQ program completion

    The Feasibility of Intervention will be administered to healthcare providers to assess the potential utility and modifications needed for the developed implementation strategies. This brief 4-item questionnaire was designed to test implementation outcomes related to program feasibility. This questionnaire is considered a strong indicators of future implementation success and will be used to inform modifications for large scale testing of implementation processes in future research. Items on this assessment are routinely modified to match the specific implementation programming, and for this study were modified slightly to gauge healthcare provider perceptions of vaping assessment and referral processes to This is Quitting

  • E-cigarette expectanciesBaseline

    Similar to the framework used by Harrell et al. positive (e.g., negative affect reduction, stimulation/state enhancement, stress reduction) and negative consequences (e.g., cost, addiction) associated with e-cigarette use will be evaluated using a 15-item questionnaire derived from the Smoking Consequences Questionnaire-Adult (SCQ-A). In addition items related to having had cancer were included in the questionnaire in line with prior research (e.g., "E-cigarettes help me reduce cancer-related stress."). Response options range on a 7-point Likert scale from "very strongly disagree" to "very strongly agree.

  • Patient-Provider E-Cigarette CommunicationBaseline

    Motivation and contemplation to quit assess how motivated someone is to quit e-cigarettes (not all motivated to very motivated)

  • Prior history of e-cigaretteBaseline; 1-week post TIQ program completion

    Prior history of e-cigarette quitting behaviors assesses how many times a participant has tried to quit (yes/no; if yes, how many quit attempts)

  • Patient Preferences for E-Cigarette Use Assessment and Referral Processes.Baseline

    Semi-structured interviews will assess preferences for assessment of e-cigarette use within oncology clinic settings and referral for cessation programs.

  • Healthcare Provider Perceptions of Barriers to E-Cigarette Assessment and Referral Processes.Baseline

    Questionnaires will assess current processes and barriers to vaping assessments and referral to cessation programs, as well as information needs, preferences, and required tools.

  • Healthcare Provider Post-Intervention InterviewsPhase 2, 4-weeks post implementation

    Interviews will assess provider experience, barriers, and facilitators of developed implementation strategies

  • Healthcare Provider Perspectives of Program Implementation PotentialPhase 2, 4 weeks Post-Implementation

    The Feasibility of Intervention will be administered to healthcare providers to assess the potential utility and modifications needed for the developed implementation strategies. This brief 4-item questionnaire was designed to test implementation outcomes related to program feasibility. This questionnaire is considered a strong indicator of future implementation success and will be used to inform modifications for large scale testing of implementation processes in future research. Items on this assessment are routinely modified to match the specific implementation programming, and for this study were modified slightly to gauge healthcare provider perceptions of vaping assessment and referral processes to This is Quitting

  • Healthcare Provider Attitudes, Beliefs, Knowledge, and Communication about E-cigarettesBaseline

    Items were modified from previous research to assess patient-doctor communication surrounding e-cigarette use including interest, comfort, and importance of these discussions. Questions also assessed for discussions related to use, referral for quitting support, and attitudes/beliefs about e-cigarette risk.

  • Patient-Provider E-Cigarette Communication1-week post TIQ program completion

    The Acceptability of Intervention Measure and Intervention Appropriateness Measures will be administered to evaluate implementation potential of the vaping cessation program. These brief 4-item questionnaires were designed to test implementation outcomes related to program acceptability and appropriateness. They are considered strong indicators of future implementation success and will be used to inform modifications. Items on this assessment are routinely modified to match the specific implementation programming, and for this study were modified slightly to gauge participant perceptions of This is Quitting.

  • Satisfaction Survey1-week post TIQ program completion

    This survey will evaluate patient participant perspectives on satisfaction of TIQ programming including types of messages and frequency of messaging, and the degree the program was helpful in reducing vaping.