Comparing Pain Management for Abdominal Aortic Surgery
This study is comparing two ways to manage pain after major abdominal surgery for conditions like aortic aneurysms. Researchers are looking at whether a single injection of a pain medicine mixture (liposomal bupivacaine and bupivacaine) works as well as, or better than, the current standard treatment, which involves continuous pain medicine (ropivacaine) delivered through small tubes (catheters). They want to see if the new approach is safe and practical, and how it affects the cost of care, complications, and nausea after surgery. You might be able to join if you are between 18 and 80 years old, speak English, and are having elective vascular surgery with an open abdominal incision. The study is currently recruiting a small number of participants, with 14 planned.
- Study design
- This is an interventional study comparing two different pain management approaches. It is a pilot study, meaning it's a small-scale test with 14 planned participants.
- What's involved
- Participants will receive either a single dose of pain medication or continuous pain medication through catheters during surgery. The study will track your experience until discharge or up to one week.
- Compensation
- Not stated in the trial record.
- Follow-up
- Researchers will track your cost of care during hospitalization (up to 2 weeks), complications (up to 1 week), and nausea and vomiting (up to 96 postoperative hours).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Liposomal Bupivacaine/Bupivacaine in Rectus Sheath Blocks Versus Ropivacaine in Rectus Sheath Blocks And Catheters
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Kevin Finkel, MD · PRINCIPAL_INVESTIGATOR · Hartford Hospital
Who to contact
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What this trial measures
- The cost of care during hospitalization.From the time of the blocks until the date of discharge, assessed as 2 weeks
To compare the resources consumed by each intervention from many different perspectives (e.g. anesthesia staff cost per time spent to perform the study intervention and the successive daily evaluations, facility cost per length of stay, block and catheter medication cost, block and catheter supply cost.)
- The occurrence of block-related and catheter-related complications, or local anesthetics-related adverse events up to hospital discharge or up to one week.From the date of the block until the date of discharge, assessed up to 1 week
Determine whether patients receiving ropivacaine in rectus sheath catheter versus Bupivacaine/Liposomal Bupivacaine in rectus sheath block have any difference in the occurrence of any related complications or adverse events up to hospital discharge or up to one week.
- Postoperative nausea and vomitingUp to 96 postoperative hours
Compare the occurrence of postoperative nausea and vomiting using the Simplified Postoperative Nausea and Vomiting Impact Scale which consists of two questions, with a possible response total score of 0-6. Response score totals of 0-2 require no intervention. Response score totals of 3-4 may necessitate antiemetic medication. Response score totals of 5-6 are considered clinically important nausea requiring medication intervention, as this would constitute patients with excessive vomiting. This scale will be used daily through the duration of in-hospital care (1-7 days)