Understanding Fasting's Impact on Hypoglycemia in Type 1 Diabetes
This study is looking at how fasting affects your body's response to low blood sugar (hypoglycemia) if you have type 1 diabetes. Researchers want to see if fasting changes how your body produces hormones like glucagon and glucose from your liver, which are important for raising blood sugar. You might be able to join if you are 18-45 years old, have type 1 diabetes, and are not obese. The study will compare what happens when you fast before experiencing insulin-induced hypoglycemia versus when you eat normally. The main goal is to see if fasting makes it harder for your body to recover from low blood sugar. The study is currently unclear on its recruitment status and plans to enroll 10 participants.
- Study design
- This is an interventional study, meaning participants will receive specific interventions (fasting or feeding) before experiencing insulin-induced hypoglycemia. It plans to enroll 10 participants.
- What's involved
- Participants will undergo procedures where they are either fasted or eat normally before insulin is given to induce low blood sugar. Measurements will be taken during these procedures, up to 2.5 hours.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements of glucagon, hepatic glucose production, and glucose infusion rate will be taken during the procedure, up to 2.5 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- GlucagonDuring procedure, up to 2.5 hours
From plasma
- Hepatic glucose productionDuring procedure, up to 2.5 hours
From plasma
- Glucose infusion rateDuring procedure, up to 2.5 hours
Amount of glucose required to maintain glycemia at \~55 mg/dL.