Study of INS018_055 for Idiopathic Pulmonary Fibrosis

This study is testing a new medication called INS018_055 for people with Idiopathic Pulmonary Fibrosis (IPF). IPF is a serious lung disease that makes it hard to breathe. Current treatments can have side effects, so researchers are looking for new options. INS018_055 works by targeting a specific protein called RAF. In this study, some participants will receive INS018_055 as a tablet, and others will receive a placebo (an inactive tablet). The main goal is to see how safe INS018_055 is over 12 weeks by tracking any side effects. You may be able to join if you are at least 40 years old and have a diagnosis of IPF. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll 40 participants. It compares INS018_055 tablets to placebo tablets.
What's involved
You would take either INS018_055 or a placebo tablet. Your safety will be monitored from Day 1 up to Week 12.
Compensation
Not stated in the trial record.
Follow-up
Your safety will be monitored up to Week 12 (End of Treatment).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05975983

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

Recruiting
PHASE2Ages 40+InterventionalTreatment
InSilico Medicine Hong Kong Limited
~40 participants
Updated 2025-11-12 on ClinicalTrials.gov
What's tested:INS018_055Placebo

At a glance

Recruiting sites
12 of 12 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of subjects who have at least 1 treatment-emergent adverse event (TEAE)
Measured over Day 1 (Visit 2) up to Week 12 (End of Treatment (EOT))
Idiopathic Pulmonary Fibrosis (IPF)

NCT05975983

Where you'd take part

This study runs at 12 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Bogan Sleep Consultants, LLC

    Columbia, South Carolinano site contact published

    Recruiting

  • Central Florida Pulmonary Group, P.A. (CFPG) - Downtown Orlando

    Orlando, Floridano site contact published

    Recruiting

  • Florida Lung Asthma and Sleep Specialist

    Celebration, Floridano site contact published

    Recruiting

  • HonorHealth Research Institute

    Scottsdale, Arizonano site contact published

    Recruiting

  • Keck School of Medicine of USC

    Los Angeles, Californiano site contact published

    Recruiting

  • Metroplex Pulmonary and Sleep Center

    McKinney, Texasno site contact published

    Recruiting

  • Research Centers of America

    McKinney, Texasno site contact published

    Recruiting

  • Southeastern Research Center

    Winston-Salem, North Carolinano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Opens a ready-to-send draft in your own email app — review before sending.

  • Percentage of subjects who have at least 1 treatment-emergent adverse event (TEAE)Day 1 (Visit 2) up to Week 12 (End of Treatment (EOT))