NeuroPathways Intervention for Brain Tumor Patients

This study is testing a program called the NeuroPathways Intervention for people recently diagnosed with a malignant (high-grade) brain tumor. The program includes an information guide and four one-on-one coaching sessions to help you cope with your diagnosis. Researchers want to see if this program is practical to carry out and if patients find it helpful. You would use the guide, attend coaching sessions, and complete short surveys at three different times. Some participants may also be asked for feedback through exit interviews. This study is currently unclear on its status, and plans to enroll 50 participants.

Study design
This is a pilot randomized controlled trial, meaning participants will be randomly assigned to different groups. It plans to enroll 50 participants.
What's involved
You would take part in coaching sessions, use an information guide, and complete short surveys at three different points in time. Some participants will also share feedback through exit interviews.
Compensation
Not stated in the trial record.
Follow-up
The main goals of the study will be measured at 2 years.

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NCT05976490

NeuroPathways Intervention for Brain Tumor Patients

Recruiting
NAAges 18+InterventionalSupportive care
Massachusetts General Hospital
~50 participants
Updated 2025-12-17 on ClinicalTrials.gov
What's tested:Information and Support InterventionUsual supportive care

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of the Intervention: Percentage of Eligible Patients Who Enroll and Participate in the Intervention
Measured over 2 years
+1 more outcome measured
Malignant Brain Tumor
Glioma
Coping Skills
1 sites across 1 states
Massachusetts1
  • Deborah A Forst, MD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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Eligibility criteria

Inclusion

Age ≥18
Massachusetts General Hospital Cancer Center patient
Within 6 weeks of diagnosis with a primary malignant brain tumor
Able to speak and read in English

Exclusion

Inability to provide informed consent as assessed by the study team (e.g., due to neurological impairment such as severe cognitive impairment/dementia or moderate-to-severe receptive aphasia)
Deemed inappropriate to approach by patient's oncologist or study PI
  • Feasibility of the Intervention: Percentage of Eligible Patients Who Enroll and Participate in the Intervention2 years

    The investigators will assess feasibility by examining the percentage of eligible patients who agree to enroll in the study and the percentage of enrolled patients who participate in all four intervention sessions. The intervention will be deemed feasible if at least 60% of eligible patients enroll in the study and if at least 60% of enrolled patients complete all four sessions.

  • Acceptability of the Intervention: Percentage of Participants who Have High Satisfaction with the Intervention2 years

    The investigators will assess acceptability via examining the distribution of patient scores for the 8-item Client Satisfaction Questionnaire (CSQ-8). CSQ-8 scores range from 8 to 32, with higher scores indicating higher satisfaction. The intervention will be deemed acceptable if at least 80% of patients score at least 20 points on the CSQ-8.