NCT05979441

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

Enrolling by Invitation
PHASE3Ages 18+InterventionalTreatment
argenx
~240 participants
Updated 2026-07-21 on ClinicalTrials.gov
What's tested:Efgartigimod PH20 SC

At a glance

Recruiting sites
0 of 92 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of AEs, SAEs and AESIs over time
Measured over Up to 53 months
Myositis
Active Idiopathic Inflammatory Myopathy
Dermatomyositis
Polymyositis
Immune-Mediated Necrotizing Myopathy
Antisynthetase Syndrome
92 sites across 42 states
China7
Italy7
Germany6
Japan6
Georgia5
Thailand5
California3
Florida3

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Has completed trial ARGX-113-2007
Being capable of providing signed informed consent and complying with protocol requirements
Agrees to use contraceptive measures consistent with local regulations and women of childbearing potential must have a negative urine pregnancy test at baseline before receiving the study drug

Exclusion

Intention to have major surgery during the study period or any other medical condition that has arisen since enrollment in study ARGX-113-2007, that in the investigator's opinion, would confound the results of the study or put the participant at undue risk
Known hypersensitivity reaction to the study drug or 1 of its excipients
Development of any malignancy, either new or recurrent, other than basal cell carcinoma of the skin, regardless of relatedness
  • Incidence of AEs, SAEs and AESIs over timeUp to 53 months

    AE : adverse event ; SAE : serious adverse event ; AESI : adverse event of special interest.