BE WELL With Migraine: Brain Education and WELLness With Migraine

This study, called "BE WELL With Migraine," is testing two different non-drug, virtual programs to help people with migraine. Both programs, called Brain Education and WELLness with Migraine Group A and Group B, involve 8 weekly online group sessions with an instructor and access to an online platform with more learning materials. You might be able to join if you are at least 18 years old, have migraine 4-20 days a month for at least a year, and have significant headache-related disability. The study will measure how much your migraine-related disability changes after 8 weeks. This study is currently unclear about its recruitment status and aims to enroll 286 participants.

Study design: This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 286 participants.
What's involved: You would participate in 8 weekly online classes, complete an initial online screen, and have a phone or video call for a baseline assessment. You will also keep an online daily headache log and complete several online surveys throughout the study.
Compensation: Not stated in the trial record.
Follow-up: The primary outcome is measured immediately post-intervention at 8 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

BE WELL With Migraine: Brain Education and WELLness With Migraine

Recruiting

NAAges 18+InterventionalSupportive care

Wake Forest University Health Sciences

~286 participants

Updated 2026-06-12 on ClinicalTrials.gov

What's tested:Brain Education and WELLness with Migraine Group ABrain Education and WELLness with Migraine Group B

At a glance

Recruiting sites

1 of 3 listed sites are recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Disability assessed using monthly Migraine Disability Assessment (mMIDAS) - Change in Migraine Disability from baseline to 8 weeks

Measured over Immediately post-intervention at 8 weeks

Conditions

Migraine

Where it's being run

3 sites across 3 states

Massachusetts1

North Carolina1

Ohio1

Study leadership

Rebecca E Wells, MD, MPH · PRINCIPAL_INVESTIGATOR · Wake Forest University Health Sciences

Who to contact

Nicole Tamol

[email protected]

336-978-1362

Email the study team

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Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

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Eligibility criteria

Inclusion

Diagnosis of migraine with or without aura by with headache frequency of 4-20 days/month

At least 1 year of migraine

At least 18 years old

Able to participate in 8 weekly online classes

Willingness to complete baseline headache logs

Headache-related disability (Headache Impact Test (HIT)-6) score \>50

Fluent in English

Completion of technology onboarding with the online platform

Pregnant women who are less than or equal to 16 weeks gestation at enrollment are allowed to participate

Exclusion

Major unstable medical/psychiatric condition that could be unsafe for participants or for the group environment.

Medication overuse headache, with migraine treatment

Pregnant women who are more than 16 weeks gestation at enrollment

Unstable migraine treatment at enrollment: any preventive treatment (oral or injectable medication or neuromodulatory device) started within 12 weeks OR acute treatment within 4 weeks to ensure stability

Unwillingness to maintain stable current medication dosages for study duration

Failure to complete baseline headache logs

Heavy alcohol and illicit drug use

Participation in another intervention clinical trial or one that would interfere in this study

Experience with stress reduction training (daily meditation practice, regular use of a mindfulness app, or prior experience with MBSR)

Any, and all other diagnoses or conditions which, in the opinion of the site investigator, would prevent the patient from being a suitable candidate for the study or interfere with the medical care needs of the study participant: COVID-positive test within 30 days of enrollment

What this trial measures

Disability assessed using monthly Migraine Disability Assessment (mMIDAS) - Change in Migraine Disability from baseline to 8 weeksImmediately post-intervention at 8 weeks
Most frequently used headache disability measure developed by Dr. Richard Lipton that captures both presenteeism and absenteeism. Although originally developed to report the prior 3 months, the monthly MIDAS ("mMIDAS") reduces recall bias and improves validity.

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