This study, called "Genomic Uniformed-Screening Against Rare Disease In All Newborns," is looking at how using genome sequencing (a test that looks at all of a baby's genes) can help expand the number of conditions screened for in newborns. Currently, all babies get a routine newborn screening test. This study invites families to have their newborn baby screened for additional genetic conditions beyond the standard screening. You can choose to be part of the study or just have the routine screening. We are looking for newborns admitted to certain hospital nurseries, born after 33 weeks of pregnancy, whose parents speak English, Mandarin, or Spanish. The study aims to see how many families join, how often sequencing is successful, and how many babies screen positive for these additional conditions.

Study design

This is an interventional study planning to enroll 100,000 newborns. It is not specified if it is randomized or blinded.

What's involved

Dried blood spots collected at birth for routine newborn screening will be used for genome sequencing-based screening.

Compensation

Not stated in the trial record.

Follow-up

The study will measure enrollment rates from launch to the end of enrollment (up to 5 years), and sequencing and screen positive rates up to 6 months after enrollment ends.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.