Observational Study on Racial and Socioeconomic Differences in Chronic Low Back Pain

This research study aims to understand how your racial background and socioeconomic status (like income, education, and job) might affect your experience with chronic low back pain (cLBP). Researchers are looking to see if there are differences in symptoms, how you react to pain, and other related factors among different racial groups. You may be able to join if you are between 18 and 85 years old and have had non-specific cLBP for at least three months, with pain on most days in the past six months. The study will measure these differences over two years to see if there are disparities. The current recruitment status for this study is unclear.

Study design
This is an observational study planning to include 240 participants. It is not testing a specific treatment, but rather observing differences.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be observed for two years to measure the primary outcomes.

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NCT05991440

Examining Racial and Socioeconomic Differences in Chronic Low Back Pain

Recruiting
Not specifiedAges 18–85Observational
Washington University School of Medicine
~240 participants
Updated 2026-07-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.
Measured over two years
+2 more outcomes measured
Chronic Pain
1 sites across 1 states
Missouri1
  • Burel Goodin, PhD · PRINCIPAL_INVESTIGATOR · Washington University School of Medicine

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Eligibility criteria

Exclusion

Participants report ethnic group as non-Hispanic and racial group as either Black/African American or White/Caucasian.
Low back pain that is attributable to other factors such as ankylosing spondylitis, infection, malignancy, compression fracture of other trauma.
Systemic rheumatic disease/condition (e.g. rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia).
Any other chronic pain condition that the participant believes to be more prominent or severe than the low back pain.
A history of clinically significant surgery to the low back within the past year.
Uncontrolled hypertension (i.e. SBP/DBP of \> 150/95), cardiovascular or peripheral arterial disease.
Poorly controlled diabetes (HbA1c \> 8%).
Neurological disease (e.g. Parkinson's, multiple sclerosis, epilepsy).
Serious psychiatric disorder requiring hospitalization within the past 12 months or characterized by active suicidal ideation.
Diminished cognitive function that would interfere with understanding of study procedures.
  • To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.two years

    Clinical pain severity will be observed through quantitative sensory testing and self-reported questionnaires and surveys.

  • To elucidate racial group disparities in experimental pain sensitivity among NHBs and NHWs with cLBP.two years

    Quantitative sensory testing equipment and biological markers assayed via blood samples.

  • To elucidate racial group disparities in psychosocial risk factors, among NHBs and NHWs with cLBP.two years

    Psychosocial risk factors that will be observed will be greater increases in depressive symptoms, anxiety, and perceived stress, as well as greater social isolation and loneliness through the use of self-reported questionnaires and surveys.