Observational Study of Lymphovenous Bypass Procedure to Prevent Lymphedema

This study is looking at whether a procedure called lymphovenous bypass (LVB) can help prevent lymphedema (swelling caused by fluid buildup) in people who are having lymph nodes removed from their groin or pelvis (inguinal lymphadenectomy or pelvic lymphadenectomy). Researchers want to see if performing LVB at the same time as lymph node removal can stop lymphedema from developing. You may be able to join if you are 18 or older, are having these lymph node removal surgeries, and are willing to participate. The main goal is to track any side effects you might experience. This is an observational study, meaning researchers will watch what happens to a small group of 20 participants.

Study design
This is an observational study with a planned enrollment of 20 participants. It is not specified if it is randomized or blinded.
What's involved
You will have the lymphovenous bypass procedure during your surgery. You will then return to the clinic for leg measurements 14 days, 6 months, 12 months, 18 months, and 24 months after your surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed through study completion, which is an average of 1 year, to track adverse events.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05992909

Prophylactic Lymphovenous Bypass Procedure Following Inguinal Lymphadenectomy or Pelvic Lymphadenectomy: A Prospective Observational Study

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~20 participants
Updated 2026-06-16 on ClinicalTrials.gov
What's tested:Lymphovenous bypass procedure

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 4.03
Measured over through study completion; an average of 1 year
Lymphadenectomy
1 sites across 1 states
Texas1
  • Ashleigh Francis, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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  • Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 4.03through study completion; an average of 1 year