Comparing PET/CT and Cardiac CT for Coronary Artery Disease
This study is looking at new ways to detect coronary artery disease (CAD), a condition where plaque builds up in the heart's arteries. Researchers want to compare a special type of scan called NaF-PET/CT with standard heart CT scans. They believe NaF-PET/CT might be better at finding early signs of plaque buildup. The study will involve 33 patients who are suspected of having CAD and are already scheduled for a heart CT scan. You could be eligible if you are 18 or older, have symptoms that suggest CAD, and are referred for a coronary CT angiography. The main goal is to see how well NaF-PET/CT can measure the amount of plaque compared to other CT scans, and how accurate it is at finding coronary atherosclerosis.
- Study design
- This is an interventional study comparing two diagnostic tests in 33 participants. It is a single-center, prospective diagnostic accuracy study.
- What's involved
- Participants will undergo an additional NaF-PET/CT scan in addition to their clinically indicated cardiac CT scan. The primary endpoints are measured at 60 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study measures outcomes at 60 days after the scans.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Armin Zadeh, MD PhD MPH · PRINCIPAL_INVESTIGATOR · Johns Hopkins School of Medicine
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Correlation of atheroma volume [mm3]60 days
Coronary atheroma volume by PET/CT vs. CT total atheroma volume
- Diagnostic accuracy of detecting coronary atherosclerosis60 days
PET/CT Sensitivity to detect any atherosclerosis by CT angiography