Neuromodulation for OCD

This study is testing a new, non-invasive treatment for Obsessive-Compulsive Disorder (OCD) called high definition transcranial alternating current stimulation. This treatment delivers a low-intensity electrical current to a specific brain area (the orbitofrontal cortex, or OFC) to help reduce OCD symptoms. Researchers are looking for 90 adults, aged 18 or older, who have been diagnosed with OCD and have a YBOCS score of 16 or higher. You cannot participate if you have a history of bipolar disorder, psychotic disorders, Tourette syndrome, psychosurgery, or substance abuse. The main goal is to see if this treatment can reduce OCD symptoms, measured by the YBOCS score, after 5 days of intervention. Early results have been encouraging, showing quick and lasting symptom reduction.

Study design
This study plans to enroll 90 participants to test a device called high definition transcranial alternating current stimulation for OCD.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at day 5 of the intervention, but the record also mentions preliminary data showing effects lasting 1-3 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05994053

Neuromodulation for a Novel OCD Biomarker and Treatment

Recruiting
NAAges 18+InterventionalTreatment
Boston University Charles River Campus
~90 participants
Updated 2026-07-23 on ClinicalTrials.gov
What's tested:high definition transcranial alternating current stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
YBOCS
Measured over day 5 of intervention
OCD
1 sites across 1 states
Massachusetts1

Opens a ready-to-send draft in your own email app — review before sending.

  • YBOCSday 5 of intervention

    There are 10 YBOCS questions scored 0 to 4. The total Y-BOCS score is the sum of items 1-10. A higher score is worse.