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Suicide Prevention for Homeless Youth Using Substances

This study is looking for young people (ages 15-24) experiencing homelessness who have recently thought about suicide or attempted it, and also use alcohol or drugs. It aims to find out if a program called Cognitive Therapy for Suicide Prevention (CTSP) can help reduce suicidal thoughts. Participants will either receive 10 sessions of CTSP (with 9 optional extra sessions) along with their usual community services, or just their usual community services. Researchers will measure suicidal thoughts at different times over 12 months to see if CTSP is effective. The study hopes to find a good way to help young people who are homeless and use substances, as suicide is a major concern for this group.

Study design
This interventional study plans to enroll 300 participants. It compares two groups: one receiving Cognitive Therapy for Suicide Prevention plus usual care, and another receiving only usual care.
What's involved
Participants will attend 10 sessions of Cognitive Therapy for Suicide Prevention, with 9 optional booster sessions, or receive their usual community services. Suicidal thoughts will be measured at baseline, 3, 6, 9, and 12 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after starting the study, with measurements taken at 3, 6, 9, and 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05994612

Suicide Prevention for Substance Using Youth Experiencing Homelessness

Recruiting
NAAges 15–24InterventionalPrevention
Ohio State University
~300 participants
Updated 2026-04-16 on ClinicalTrials.gov
What's tested:Cognitive Therapy for Suicide PreventionServices as Usual

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Suicidal Ideation: Scale for Suicidal Ideation-Worst Point (SSI-W)
Measured over baseline, 3, 6, 9 and 12 months

Conditions

Suicide Prevention

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Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • The Ohio State University

    Columbus, Ohiostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Natasha Slesnick · PRINCIPAL_INVESTIGATOR · Ohio State University

Who to contact

Natasha Slesnick, PhD
[email protected]
6142478469
Email the study team

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Eligibility criteria

Inclusion

15-24 years
SSI-W score \> 4 or at least one suicide attempt in prior 12 months
Meets criteria for homelessness
At least four uses of alcohol/drugs in prior 30 days

Exclusion

Youth requires psychiatric hospitalization

What this trial measures

  • Suicidal Ideation: Scale for Suicidal Ideation-Worst Point (SSI-W)baseline, 3, 6, 9 and 12 months

    Change in suicidal ideation is measured using the Scale for Suicidal Ideation-Worst Point (SSI-W). Each item consists of three options, which are rated on a 3-point scale from 0 to 2, and each item is graded according to the intensity of the suicidality. Total scores are calculated by summing the 19 ratings, and these total scores can range from 0 to 38 with higher scores indicating worse severity.