This study aims to understand how people with familial partial lipodystrophy (FPLD), a condition where the body doesn't store fat normally, process fat compared to healthy individuals. Researchers will assess the feasibility of taking small fat tissue samples (biopsies) from different body areas, specifically the thigh and abdomen, in people with FPLD. They also want to see if they can detect special "labeled" fats in these samples after participants drink "heavy water." This will help them learn more about how fat is stored and used in FPLD, which could lead to better ways to manage related health issues like diabetes and heart disease. The study plans to enroll 14 participants, including those with FPLD and healthy volunteers, aged 18 to 65.

Study design

This is an observational study involving 14 participants, including those with FPLD and healthy controls. It is not specified if it is randomized or blinded.

What's involved

You would undergo screening, a physical exam, body measurements, and an imaging scan. You would also drink heavy water at home and have fat tissue biopsies from your abdomen and thigh.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoints are measured at 10 days after the procedures.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.