Artificial Tears for Tear Duct Obstruction in Thyroid Cancer Patients
This study is investigating whether using artificial tears (methylcellulose) can prevent a condition called nasolacrimal duct obstruction (NLDO) in people receiving radioactive iodine for thyroid cancer. NLDO is when your tear duct gets blocked, which can happen after radioactive iodine treatment. Researchers believe radioactive iodine might get into tears and cause inflammation, leading to blockages. This study will see if using artificial tears helps reduce this problem. You may be able to join if you are 18 or older, have thyroid cancer, and are receiving a high dose (150 mCi or more) of radioactive iodine therapy. The main goal is to see how many people develop NLDO after two years.
- Study design
- This is an interventional study planning to enroll 100 participants. It is not specified if it is randomized or blinded.
- What's involved
- Participants will self-administer artificial tears according to a schedule. The trial record does not specify other visits, procedures, or tests.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for the incidence of NLDO for two years after radiotherapy.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Incidence of Post-Radiotherapy Nasolacrimal Duct Obstruction (NLDO)2 years
The rate of patients that developed NLDO after radioactive iodine therapy in each experimental group as determined by tear duct irrigation by an ophthalmologist.