Enhancing Memory in CPT for PTSD

This study is looking at ways to improve Cognitive Processing Therapy (CPT) for older Veterans with Post-Traumatic Stress Disorder (PTSD). CPT is a type of talk therapy. Researchers want to see if adding "Memory Support" strategies to CPT helps people learn and remember the therapy content better, which could lead to better treatment results. You might be able to join if you are a Veteran over 59 years old with a PTSD diagnosis. The study will compare standard CPT to CPT with Memory Support. Success will be measured by changes in your PTSD symptoms, using a tool called the PTSD Checklist-5 (PCL-5), measured through the end of treatment (12-16 weeks). The current status of this study is unclear, and it plans to enroll 30 participants.

Study design
This is an interventional study, but the phase is not specified. It plans to enroll 30 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your PTSD symptoms will be measured through study completion, which is 12-16 weeks of treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06000475

Enhancing Memory in Cognitive Processing Therapy for PTSD

Recruiting
NAAges 60+InterventionalTreatment
VA Office of Research and Development
~30 participants
Updated 2026-07-30 on ClinicalTrials.gov
What's tested:Cognitive Processing TherapyCognitive Processing Therapy (CPT) + Memory Support

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PTSD Checklist-5 (PCL-5)
Measured over Through study completion, weeks 12-16 of treatment
Stress Disorders, Post-Traumatic
1 sites across 1 states
Pennsylvania1
  • James C. Scott, PhD · PRINCIPAL_INVESTIGATOR · Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Veterans with DSM-5 diagnoses of PTSD via the Clinician Administered PTSD Scale (CAPS-5)

Exclusion

daily benzodiazepine use (due to memory impairing effects)
bipolar or psychotic disorders
current suicidal ideation with plan or intent
current moderate or severe substance use disorder not in remission for \>1 month
severe traumatic brain injury
a Montreal Cognitive Assessment (MoCA) indicative of dementia
or other disorders that would severely limit study participation
  • PTSD Checklist-5 (PCL-5)Through study completion, weeks 12-16 of treatment

    Questionnaire for symptoms of PTSD; the range of the scale is from 0 (no symptoms) to 80 (maximal symptoms)