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Study of C7 Nerve Transfer for Stroke-Related Arm Weakness

This study is looking at how a surgery called contralateral C7 root transfer can help people who have arm weakness (spastic hemiparesis) after a stroke. This surgery involves moving a nerve from one side of your neck to the other to help improve arm function. You might be able to join if you are between 18 and 65 years old, have had an ischemic (clot-related) or hemorrhagic (bleed-related) stroke, and your arm weakness hasn't improved much with rehabilitation in the last 1-5 years. We will measure success by looking at changes in your arm function using a special scale. The current status of this study is unclear, and it plans to enroll about 95 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 95 participants.
What's involved
You would have surgery and then follow-up visits at 2, 4, 8, and 12 months after the surgery to measure your arm function.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after the surgery to assess changes in arm function.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06001736

Utility of CC7 Transfer in Stroke Subtypes

Recruiting
NAAges 18–65InterventionalTreatment
Dartmouth-Hitchcock Medical Center
~95 participants
Updated 2026-02-27 on ClinicalTrials.gov
What's tested:Contralateral C7 root transfer for the treatment of spastic hemiparesis.

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in arm function, as measured by the Fugl-Meyer upper-extremity scale.
Measured over 12 months with visits at baseline and months 2, 4, 8, and 12 months after surgery.

Conditions

Stroke, Ischemic
Stroke Hemorrhagic
Spastic Hemiparesis

Explore related trials

Hemorrhagic StrokeIschemic StrokeSpastic Hemiplegia

Where it's being run

1 sites across 1 states
New Hampshire1

Study leadership

  • Jennifer Hong, Dr. · PRINCIPAL_INVESTIGATOR · Dartmouth-Hitchcock Medical Center

Who to contact

Lauren Sinks
[email protected]
(603) 653-9021
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

History of ischemic or hemorrhagic stroke with resultant arm paresis that has ceased to improve within 1-5 years of rehabilitation.
baseline Fugl-Meyer score below 33

Exclusion

pregnancy

What this trial measures

  • Change from baseline in arm function, as measured by the Fugl-Meyer upper-extremity scale.12 months with visits at baseline and months 2, 4, 8, and 12 months after surgery.

    The Fugl-Meyer is a widely used and highly recommended stroke-specific, performance-based measure of impairment with 5 domains and a possible 226 points.