Personalized Cognitive Training for Mild Cognitive Impairment

This study is testing a personalized computer-based cognitive training program called pSOPT. This program adjusts its difficulty based on your heart rate and how well you're doing, to help you train at your best. We are also comparing it to another computer activity called MLA, which includes games like cross-word puzzles and Sudoku. We are looking for about 50 participants aged 60 and older who have mild cognitive impairment or subjective cognitive impairment (memory concerns). The main goal is to see if pSOPT can improve your overall thinking abilities. The study status is currently unclear.

Study design
This is an interventional study with a planned enrollment of 50 participants. It is testing two behavioral interventions: pSOPT and MLA.
What's involved
Your cognitive measures will be assessed at the beginning of the study, after 7 weeks, and again at 3 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 3 months after the start of the study.

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NCT06005038

CogT pSOPT Intervention Study

Recruiting
PHASE1Ages 60+InterventionalPrevention
Stanford University
~50 participants
Updated 2024-05-17 on ClinicalTrials.gov
What's tested:pSOPTMLA

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
composite cognitive measure
Measured over Baseline, Week 7, and 3-month
Mild Cognitive Impairment
Subjective Cognitive Impairment
1 sites across 1 states
California1

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  • composite cognitive measureBaseline, Week 7, and 3-month

    a composite score of episodic memory and executive function. Episodic memory will be assessed using the Rey Auditory Verbal Learning and Brief Visuospatial Memory tests. Alternative forms of the tests will be used to reduce practice effects.The Z-transform scores across all assessment points within each test will be developed first to derive 2 composite scores (learning and delayed recall). Executive function will be measured using the EXAMINER, a computerized test package designed for RCTs. It includes 8 tests and calculates 4 sub-domain composite scores on working memory (Dot counting and N-back), inhibition (Flanker, Continuous Performance Test, and Anti-saccades), cognitive control (Dimensional Set Shifting), and Fluency (Phonemic Fluency and Category Fluency), and an overall composite score for executive function. A composite score synthesizing EXAMINER composite score, learning, and delayed recall will be created; higher indicates better performance.