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Rehabilitation Using Robotics and Neuromuscular Modeling for Stroke Survivors

This study is exploring new ways to improve walking after a stroke. Researchers are testing different rehabilitation methods using a treadmill with special features. These include "Belt Accelerations," where the treadmill belts speed up independently, and "Belt accelerations combined with an exoskeleton," which adds a hip support device. They are also testing a "Variable Stiffness treadmill" that changes the firmness of the walking surface. The goal is to see how these interventions affect muscle activation in your legs, specifically the plantarflexor muscle, which helps you push off the ground. The study is looking for 72 participants, including healthy individuals and stroke survivors aged 18 to 80 years old. The study aims to understand the best methods for improving walking function after a stroke.

Study design
This interventional study plans to enroll 72 participants, including healthy individuals and stroke survivors. It is not specified if the study is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints, which measure muscle activation, are assessed during the intervention itself.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06008743

Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling

UNKNOWN
NAAges 18–80InterventionalBasic science
University of Delaware
~72 participants
Updated 2023-08-24 on ClinicalTrials.gov
What's tested:Belt AccelerationsBelt accelerations combined with an exoskeletonVariable Stiffness treadmill

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Contralateral plantarflexor muscle activation during exposure to belt accelerations
Measured over During intervention
+8 more outcomes measured

Conditions

Stroke

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Stroke

NCT06008743

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Delaware

    Newark, Delawarestudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Panagiotis Artemiadis, Ph.D.
[email protected]
302-831-8546
Email the study team

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Eligibility criteria

Exclusion

Any neurological conditions (applicable to Group A - healthy subjects) or other neurological conditions in addition to stroke (applicable to Group B - stroke survivors);
Inability to walk outside the home before the stroke (applicable to Group B - stroke survivors);
Coronary artery bypass graft in the past 3 months, myocardial infarction in the past 3 months, uncontrolled or untreated atrial fibrillation, severe or painful peripheral vascular disease, diagnosis of heart failure, or unstable or untreated angina;
Expressive aphasia
Reported musculoskeletal pain or conditions that limit walking (such as tendonitis, arthritis, osteoporosis, spinal stenosis, or any orthopedic surgery or fracture to the legs or spine in the last 6 months);
Inability to communicate with investigators (e.g., due to severe aphasia or other cognitive impairment);
Severe respiratory problems such as chronic obstructive pulmonary disease (COPD);
Unexplained dizziness;
Weight greater than 250 pounds (lbs).
Inability to ascend and descend 4 steps with handrails using another person's assistance (if desired)

What this trial measures

  • Contralateral plantarflexor muscle activation during exposure to belt accelerationsDuring intervention

    Magnitude of the neural signal (in millivolts (mV) sent to three muscles during push-off, as explained via surface ElectroMyoGraphic signals, measured during exposure to belt accelerations. Three measurements (one from each relevant muscle) will be considered primary outcome measures.

  • Contralateral plantarflexor muscle activation during exposure to combined exposure to belt accelerations and exoskeleton interactionDuring intervention

    Magnitude of the neural signal (in millivolts (mV) sent to three muscles during push-off, as explained via surface ElectroMyoGraphic signals, measured during exposure to combined exposure to belt accelerations and exoskeleton interaction. Three measurements (one from each relevant muscle) will be considered primary outcome measures.

  • Contralateral plantarflexor muscle activation during exposure to lowered stiffness step perturbationDuring intervention

    Magnitude of the neural signal (in millivolts (mV) sent to three muscles during push-off, as explained via surface ElectroMyoGraphic signals, measured during exposure to lowered stiffness step perturbation. Three measurements (one from each relevant muscle) will be considered primary outcome measures.

  • Hip extension exposure to belt accelerationsDuring intervention

    Extension of the leg during push-off, measured as hip extension angle in degrees, during exposure to belt accelerations.

  • Hip extension during exposure to combined exposure to belt accelerations and exoskeleton interactionDuring intervention

    Extension of the leg during push-off, measured as hip extension angle in degrees, during exposure to combined exposure to belt accelerations and exoskeleton interaction.

  • Hip extension during exposure to lowered stiffness step perturbationDuring intervention

    Extension of the leg during push-off, measured as hip extension angle in degrees, during exposure to lowered stiffness step perturbation.

  • Step length symmetry exposure to belt accelerationsDuring intervention

    Step length symmetry, measured as a percentage of the left leg step length to the right leg step length, during exposure to belt accelerations.

  • Step length symmetry during exposure to combined exposure to belt accelerations and exoskeleton interactionDuring intervention

    Step length symmetry, measured as a percentage of the left leg step length to the right leg step length, during exposure to combined exposure to belt accelerations and exoskeleton interaction.

  • Step length symmetry during exposure to lowered stiffness step perturbationDuring intervention

    Step length symmetry, measured as a percentage of the left leg step length to the right leg step length, during exposure to lowered stiffness step perturbation.