A Study of TL118 for Solid Tumors with NTRK Gene Fusions

This study is looking at how well a drug called TL118 works and if it's safe for people with certain solid tumors. TL118 is a capsule taken by mouth. It targets specific changes in your genes (NTRK gene fusions) that can cause cancer to grow. To join, you must be 18 or older and have a solid tumor with an NTRK gene fusion. The main goal is to see how many people respond to TL118, with responses measured for up to 24 months. The study is currently unclear about its recruitment status and plans to enroll about 60 participants.

Study design
This study is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 60 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your response to treatment will be measured from before you start the drug up to about 24 months after your last dose.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06010342

A Study to Evaluate the Efficacy and Safety of TL118 in Solid Tumors Patients

Recruiting
PHASE2Ages 18+InterventionalTreatment
Teligene US
~60 participants
Updated 2026-04-28 on ClinicalTrials.gov
What's tested:TL118 Capsule

At a glance

Recruiting sites
19 of 19 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Objective Response Rate (ORR)
Measured over Pre-dose up to approximately 24 months post-dose
Solid Tumor

NCT06010342

Where you'd take part

This study runs at 19 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Adventist Health Glendale

    Glendale, Californiano site contact published

    Recruiting

  • Affiliated Cancer Hospital and Institute of Guangzhou Medical University

    Guangzhou, Guangdong, Chinano site contact published

    Recruiting

  • Affiliated Cancer Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, Chinano site contact published

    Recruiting

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, Chinano site contact published

    Recruiting

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, Chinano site contact published

    Recruiting

  • Fujian Cancer Hospital

    Fuzhou, Fujian, Chinano site contact published

    Recruiting

  • Harbin medical university cancer hospital

    Harbin, Heilongjiang, Chinano site contact published

    Recruiting

  • Hunan Cancer Hospital

    Changsha, Hunan, Chinano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Opens a ready-to-send draft in your own email app — review before sending.

  • Objective Response Rate (ORR)Pre-dose up to approximately 24 months post-dose