NCT06023407
Feasibility of Improving Glycemia With Heat Therapy to Prevent AD
Enrolling by Invitation
NAAges 65+InterventionalUniversity of Kansas Medical CenterInvestigator-initiated
~60 participants
Updated 2026-04-17 on ClinicalTrials.gov
What's tested:Water Immersion Heat Therapy
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
HbA1C
Measured over 10 weeks
+1 more outcome measured
Conditions
Where it's being run
1 sites across 1 statesKansas1
Study leadership
- Jill Morris · PRINCIPAL_INVESTIGATOR · University of Kansas Medical Center
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Age 65 and older
Stable medication doses (\>1 month)
Post-menopausal
Clinical Dementia Rating (CDR) of 0
History of or current metabolic impairment (i.e. metabolic syndrome, pre-diabetes, Type 2 Diabetes, etc)
Exclusion
Excluded from or unable to complete an MRI scan. MRI compatible pacemakers will require cardiologist clearance prior to enrolling.
ACSM Risk score stratification of "High" unless cleared by a physician prior to participation.
Myocardial infarction or symptoms of coronary artery disease in the last 2 years.
History of or current diagnosis of disorders with the potential to impair cognition (i.e. AD, Parkinson's disease, stroke (defined as clinical episode w/ neuroimaging evidence in appropriate area to explain symptoms)).
Insulin-dependent (Type 1) Diabetes Mellitus.
Clinically significant chronic disease such as cancer, HIV, or acquired immunodeficiency syndrome.
Clinically significant depressive symptoms that may impair cognition, use of psychoactive and investigational medications, and significant visual or auditory impairment.
Orthopedic complications that would preclude individuals from safely entering a hot tub.
Untreated hypothyroidism or diseases associated with heat intolerance (i.e. Graves disease, etc).
Contraindication for temperature pill ingestion (i.e. inflammatory bowel disease, diverticulitis or related).
What this trial measures
- HbA1C10 weeks
hemoglobin A1C (HbA1C) test is a blood test that shows what your average blood sugar (glucose) level was over the past two to three months. below 5.7 %. Anyone with an HbA1c. A value of 5.7 % to 6.4 % is considered to be prediabetic, while diabetes can be diagnosed with a HbA1c of 6.5% or higher.
- Insulin sensitivity index10 weeks
Using glucose and insulin from a the OGTT, an indices will be calculated for insulin sensitivity. The goal is to increase the insulin sensitivity. Minimum=0; No upper limit. Increasing value indicates improved outcomes.