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rTMS and Virtual Reality for Mild Cognitive Impairment

This study is testing if a combination of brain stimulation (rTMS, or repetitive Transcranial Magnetic Stimulation) and brain training using virtual reality (iVCT) can improve memory, mood, and daily functioning in older adults with Mild Cognitive Impairment (MCI). You might be able to join if you are 55 or older and have a previous diagnosis of MCI. The researchers want to see if this combined treatment helps more than rTMS alone or usual care. The main way they will measure success is by looking at changes in your verbal learning scores over time. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 50 participants, with 30 eligible participants being randomly assigned to one of three groups: rTMS, rTMS+iVCT, or a control group receiving usual care.
What's involved
If eligible, you would have a baseline assessment, then receive rTMS or rTMS+iVCT treatment daily for 5 days a week for 2 weeks. You would then have follow-up assessments at 2 weeks and 3 months after treatment.
Compensation
Not stated in the trial record.
Follow-up
You will be followed for 3 months after treatment to assess changes in your cognitive, emotional, and functional abilities.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06024473

A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI

Recruiting
NAAges 55+InterventionalTreatment
Central Arkansas Veterans Healthcare System
~50 participants
Updated 2025-02-20 on ClinicalTrials.gov
What's tested:rTMSrTMS+iVCT

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Hopkins Verbal Leaning Test Standard Score
Measured over baseline, 2 weeks, 3 months

Conditions

Mild Cognitive Impairment
Caregiver Burden
Mental Health Issue
ADL
Quality of Life

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NCT06024473

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Central Arkansas VA Healthcare system

    Little Rock, Arkansasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Ian Moore, PhD
[email protected]
501-257-2152
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

age 55 and over
previous diagnosis of Mild Cognitive Impairment
Score of 18 or over on the MoCA during pre-screening procedures.

Exclusion

below 55 years old
Do not pass the TMS Adult Safety Screening
Taking medications known to increase risk of seizure
Taking ototoxic medications
Those with implanted device
History of bipolar disorder
History of Tourette's syndrome or presence of motor tics
History of seizures/ seizures in first degree relatives
History of stroke, aneurysm, or cranial neurosurgery
Current alcohol related disorder needing medical treatment
History of abnormal electroencephalogram (EEG)
History of motion sickness, nausea, vomiting, seizures, or migraine
Significant balance/gait impairments/history of falls
History of hyperacusis or photophobia

What this trial measures

  • Change in Hopkins Verbal Leaning Test Standard Scorebaseline, 2 weeks, 3 months

    range: \<55 to \>130 - higher score is improvement