SMART Exercise for Peripheral Artery Disease

This study is testing different ways to help people with Peripheral Arterial Disease (PAD) walk better. It compares supervised treadmill exercise at a center, home-based exercise with coaching, and drinking nitrate-rich beetroot juice twice daily. You might be able to join if you are 50 or older and have PAD, which is defined by specific blood pressure measurements in your ankles or toes. The researchers want to see if these interventions improve how far you can walk in six minutes. The current recruitment status is unclear, but the study plans to enroll 210 participants.

Study design
This is an interventional study planning to enroll 210 participants. It compares different exercise and dietary supplement approaches for people with PAD.
What's involved
Participants will either walk on a treadmill at a center 3 times a week for 12 weeks, or walk at home with 4 in-person visits and weekly phone calls for 12 weeks, or drink beetroot juice twice daily for 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your walking distance will be measured at the beginning of the study and again after 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06032065

SMART Exercise for PAD

Recruiting
PHASE3Ages 50+InterventionalTreatment
Northwestern University
~210 participants
Updated 2026-04-15 on ClinicalTrials.gov
What's tested:Supervised Treadmill ExerciseHome-Based ExerciseNitrate-rich beetroot Juice

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Six-Minute Walk Distance
Measured over Measured at baseline and 12 week follow-up
Peripheral Arterial Disease
Aging
Peripheral Vascular Diseases
Walking, Difficulty
3 sites across 2 states
Illinois2
Minnesota1

Opens a ready-to-send draft in your own email app — review before sending.

  • Six-Minute Walk DistanceMeasured at baseline and 12 week follow-up

    Change in six-minute walk distance