NAC vs Placebo for Opioid Use After Hysterectomy
This study is looking at whether N-acetylcysteine (NAC), given through an IV, can help reduce the amount of opioid pain medication needed after a hysterectomy (surgery to remove the uterus). You could join if you are 18 or older and having an elective laparoscopic or robotic hysterectomy. Participants will receive either NAC or a placebo (an inactive substance like saline) through an IV for 60 minutes at the start of your surgery. The main goal is to see how much opioid pain medication you use in the first 72 hours after the study medication. The study aims to enroll 240 participants, but its current status is unclear.
- Study design
- This is an interventional study where participants will be randomly assigned to receive either N-acetylcysteine or a placebo. It plans to enroll 240 participants.
- What's involved
- You would receive an IV infusion of either N-acetylcysteine or placebo for 60 minutes at the start of your hysterectomy. After surgery, you will be asked to report your pain scores and any pain medication taken at various times.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your opioid consumption will be measured for 72 hours after the study medication is given.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
NAC vs Placebo on Opioid Use for Hysterectomy
At a glance
Conditions
NCT06039566
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Medical University of South Carolina
Charleston, South Carolinastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Sylvia Wilson, M.D. · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Opioid Consumption 0-72 hours post-study medication0-72 hours after study medication
72-hour post-medication opioid consumption.