This study is looking at whether giving iron supplements before surgery can help teenagers and young adults (ages 10-26) with scoliosis who are having spinal fusion surgery. Participants will either receive oral ferrous sulfate (an iron supplement) or an oral placebo tablet (a pill with no active medicine). We want to see if iron supplementation can reduce the need for blood transfusions during or after surgery, and potentially improve how well patients recover physically and mentally. To join, you need to have scoliosis or kyphosis, be able to swallow a tablet, have surgery planned in 6-24 weeks, and have low iron levels (serum ferritin less than or equal to 25 µg/L). The study is currently recruiting about 275 participants.

Study design

This is a randomized controlled trial, meaning participants will be randomly assigned to receive either the iron supplement or a placebo. The study aims to enroll 275 participants.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome, incidence of perioperative RBC transfusion, will be measured at 4 to 30 days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.