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Virtual Reality Driving Task for Vision Loss after Stroke

This study is looking at how vision loss from a stroke (cortically-induced blindness or CB) affects a person's ability to navigate, specifically when driving. Researchers want to understand how people with CB adapt and use different strategies. You would participate in a Virtual Reality (VR) Driving Task where you steer a virtual car. The main goal is to see how much your car drifts from the center of the lane in the VR simulation. This study is for adults aged 21 to 75 years old who have experienced a stroke that caused vision loss in both eyes (homonymous defects). The study plans to enroll 40 participants, but its current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 40 participants. It uses a Virtual Reality Driving Task to observe steering behavior.
What's involved
You would participate in a Virtual Reality Driving Task, steering a virtual car on a simulated roadway.
Compensation
Not stated in the trial record.
Follow-up
Your lane deviation in the Virtual Reality (VR) task will be measured on Day 0. No further follow-up is specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06047717

Vision Loss Impact on Navigation in Virtual Reality

Recruiting
NAAges 21–75InterventionalBasic science
University of Rochester
~40 participants
Updated 2026-08-25 on ClinicalTrials.gov
What's tested:Virtual Reality Driving Task

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Virtual Reality (VR) Lane Deviation / Offset
Measured over Day 0

Conditions

Stroke, Ischemic
Quadrantanopia
Hemianopsia, Homonymous
Hemianopia, Homonymous
Hemianopia
Hemianopsia
Occipital Lobe Infarct
Visual Field Defect, Peripheral
Vision Loss Partial
Quadrantanopsia
Stroke Hemorrhagic

Explore related trials

Homonymous hemianopiaHomonymous quadrant anopiaStrokeVisual Field Defect

Where it's being run

1 sites across 1 states
New York1

Who to contact

Evan Burr
[email protected]
585-275-5234
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Residents of the United States or Canada
Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and/or CT scans)
Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.
Willing, able, and competent to provide their own informed consent
Cognitively able, responsible to understand written and oral instructions in English
Emmetropic or else wear corrective contact lenses inside the virtual reality headset
Normal or corrected-to-normal vision, who are between the ages of 21 and 75 years of age, roughly matched to the age of CB subjects enrolled above
Competent and responsible, as determined by the Principal Investigator
Willing, able, and competent to provide their own informed consent
Normal cognitive abilities, be able to understand written and oral instructions in English
Emmetropic or else wear corrective contact lenses inside the virtual reality headset

Exclusion

Those who have never driven or earned a drivers' license
Past or present ocular disease interfering with visual acuity
Best corrected visual acuity (BCVA) worse than 20/40 in either eye
Sustained damage to the dorsal lateral geniculate nucleus
Presence of diffuse, whole-brain degenerative processes
Presence of brain damage deemed by study staff to potentially interfere with outcome measures
History of traumatic brain injury
Documented history of drug/alcohol abuse
Diagnosis of cognitive or seizure disorders
Diagnosis of one-sided attentional neglect
Subjects who have never driven or earned a drivers' license
BCVA worse than 20/40 in either eye
Presence of vision loss from ocular diseases or disorders
Presence of a visual field defect
Inability to wear corrective contact lenses inside the virtual reality helmet if required to see clearly
Subjects with a history of neurological disorders
Subjects with a history of TBI
Persons who lack the competence or are otherwise unable to perform the visual testing as directed.

What this trial measures

  • Virtual Reality (VR) Lane Deviation / OffsetDay 0

    Virtual lane offset is a measure of driving accuracy, which involves computing the divergence (in virtual meters) from the center of the single-lane virtual roadway, relative to the position of the driver's head and averaged over the duration of each turn. The researchers will compare the variance of lane offset in virtual meters between Cortically Blind (CB) and control subjects.