Study of TopSpin360 Training Device for Neck Strength

This study is looking at a device called TopSpin360. It's a helmet training device designed to strengthen your neck muscles to help keep your head stable during impacts. Researchers want to see if using TopSpin360 can improve neck strength and how well your brain works. They will measure changes in your neck's peak force (how much force your neck can produce), normalized peak force, and force steadiness (how consistently your neck can produce force) over about six months. You can join if you are a healthy individual between 18 and 21 years old, speak English fluently, and are medically cleared to play ice hockey. The study is currently unclear on its recruitment status and aims to enroll 60 participants.

Study design
This is an interventional study involving 60 healthy participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your neck strength will be measured at the beginning of the study and again after about six months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06052553

A Study of TopSpin360 Training Device

Recruiting
NAAges 18–21InterventionalBasic science
Mayo Clinic
~60 participants
Updated 2026-07-22 on ClinicalTrials.gov
What's tested:TopSpin360

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in peak force
Measured over Baseline, post-season (approximately 6 months)
+12 more outcomes measured
Healthy
1 sites across 1 states
Minnesota1
  • Mario Hevesi, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

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Eligibility criteria

Inclusion

Fluent English Speaker.
Medically cleared to play ice hockey.

Exclusion

Clinically documented hearing issues.
In-ear hearing aid or cochlear implant.
Implanted pacemaker or defibrillator.
Metal or plastic implants in skull. lack of verbal fluency in the English language.
History of seizures.
Allergy to rubbing alcohol or EEG gel.
  • Change in peak forceBaseline, post-season (approximately 6 months)

    Measured by a neck isometric device, maximal load in kilograms that could be applied to head before deviation from neutral position.

  • Change in normalized peak forceBaseline, post-season (approximately 6 months)

    Measured by a neck isometric device, peak force divided by participant weight in kilograms.

  • Change in force steadinessBaseline, post-season (approximately 6 months)

    Measured by a neck isometric device, average peak force.

  • Change in rate of force development (RFD)Baseline, post-season (approximately 6 months)

    Automatically collected by the TopSpin360 device, the multi-planar rate of force development (RFD) in pounds of force per second collected in both clockwise and counterclockwise.

  • Change in visuo-motor reaction timeBaseline, post-season (approximately 6 months)

    Measured by a neck isometric device, reported in milliseconds (ms)

  • Change in blood biomarker levelsBaseline, post-season (approximately 6 months)

    Blood will be at a biomarker level. We will investigate 5 different markers: NfL, SNCB, vWF, SNCA, and BDNF. Each biomarker will be measured in Nanograms per Milliliter (ng/ml).

  • Change in salivary biomarkersBaseline, post-season (approximately 6 months)

    Salivary biomarkers are relatively new and we will investigate to see if NfL, SNCB, vWF, SNCA, and BDNF. Each biomarker will be measured in Nanometer per milliliter (ng/ml).

  • Change in N100 AmplitudeBaseline, post-season (approximately 6 months)

    Electroencephalograph (EEG) recording of brain electrical activity N100 potential amplitude. This measures is subsequently linearly transformed to a standardized score on a 0-100 scale, with larger peak amplitudes and shorter peak latencies resulting in higher scores.

  • Change in N100 LatencyBaseline, post-season (approximately 6 months)

    Electroencephalograph (EEG) recording of brain electrical activity N100 potential latency. Increased latencies are indicative of slower responses. Obtained by EEG recording of N100 potential amplitude. This measures is subsequently linearly transformed to a standardized score on a 0-100 scale, with larger peak amplitudes and shorter peak latencies resulting in higher scores.

  • Change in P300 AmplitudeBaseline, post-season (approximately 6 months)

    Electroencephalograph (EEG) recording of brain electrical activity P300 potential amplitude. This measures is subsequently linearly transformed to a standardized score on a 0-100 scale, with larger peak amplitudes and shorter peak latencies resulting in higher scores.

  • Change in P300 LatencyBaseline, post-season (approximately 6 months)

    Electroencephalograph (EEG) recording of brain electrical activity P300 potential latency. Increased latencies are indicative of slower responses. This measures is subsequently linearly transformed to a standardized score on a 0-100 scale, with larger peak amplitudes and shorter peak latencies resulting in higher scores

  • Change in N400 AmplitudeBaseline, post-season (approximately 6 months)

    Electroencephalograph (EEG) recording of brain electrical activity N400 potential amplitude. Increased amplitudes are indicative of larger signals. This measures is subsequently linearly transformed to a standardized score on a 0-100 scale, with larger peak amplitudes and shorter peak latencies resulting in higher scores.

  • Change in N400 LatencyBaseline, post-season (approximately 6 months)

    Electroencephalograph (EEG) recording of brain electrical activity N400 potential latency. Increased latencies are indicative of slower responses. This measures is subsequently linearly transformed to a standardized score on a 0-100 scale, with larger peak amplitudes and shorter peak latencies resulting in higher scores.