This observational study is looking at how lung ventilation changes over one year in people with cystic fibrosis (CF). Researchers will use a special type of MRI called 19F MRI, which involves inhaling a harmless gas called perfluoropropane, to measure lung function. These measurements will be compared to other standard lung tests. The study also aims to see how these measures change if you experience a flare-up of your CF symptoms (pulmonary exacerbation) and receive treatment. You may be eligible if you are 18 years or older, a non-smoker, have a CF diagnosis, don't use supplemental oxygen, and have stable lung function. The study hopes to enroll 30 participants. Success would mean understanding how these lung measurements change over time and in response to exacerbations.

Study design

This is an observational study, meaning it looks at changes over time without assigning specific treatments. It plans to enroll 30 participants.

What's involved

You would complete 3 to 5 visits to the University of North Carolina at Chapel Hill (UNC) over one year, with each visit lasting up to 4 hours.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for changes in lung function over 14 days and up to 365 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.