Home-Based Whole-Body Vibration for Knee Osteoarthritis Pain
This study, called VIBE-Rx2, is looking at how a home-based whole-body vibration (WBV) machine affects pain and inflammation in people with knee osteoarthritis. Participants will use a personal vibration plate at home for up to 12 weeks, standing on it for up to 20 minutes at a time. Researchers want to see if this sub-acute (12 weeks) WBV training can reduce knee pain and improve blood vessel function by lowering inflammation in the body. You may be able to join if you are between 40 and 75 years old, have had knee pain from osteoarthritis for at least 6 months, and can stand for 20 minutes. The study plans to enroll 30 participants.
- Study design
- This is an interventional study with a planned enrollment of 30 participants. It is testing the effects of home-based whole-body vibration.
- What's involved
- You would use a personal vibration plate at home for up to 12 weeks, standing on it for up to 20 minutes. Your pain levels will be measured at the beginning and after 12 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain levels will be assessed at pre-treatment baseline and again after 12 weeks of whole-body vibration training.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Change in Pain Pressure Threshold assessed using the Jtech Medical Echo Algometerpre-treatment baseline and following 12 weeks sub-acute whole-body vibration
change from baseline pain pressure threshold at 12 weeks. Pain Pressure Threshold (PPT) will be assessed using the Jtech Medical Echo Algometer. PPT is used to measure deep muscular tissue sensitivity. The test determines the amount of pressure over a given area in which a steadily increasing non-painful pressure stimulus turns into an uncomfortable or painful pressure sensation. The subject will lie supine. An investigator will assess PPT at the following sites: a) 2 cm below the medial edge of the patella and b) 2 cm below the lateral edge of the patella. Using the 1 cm2 probe, the investigator will place it perpendicular to each site and apply pressure at a rate of 0.5 kg/cm2/s. Each trial will stop when the subject reports pain. The investigator will take 3 trials at each site; the average of the 3 trials, recorded in kg/cm2, will be used for statistical analysis.