Biomarkers of Reaction To HIIT Exercise for Stroke Survivors
This study is looking at how High-Intensity Interval Training (HIIT) affects walking ability in stroke survivors. HIIT involves three weekly cycling sessions for 12 weeks. Researchers want to understand why some people respond well to HIIT and others don't. They will look at factors like blood lactate (a chemical in your blood after exercise) and brain chemicals (like GABA) to predict who will improve their walking speed. This study is for Veterans aged 18 to 89 who had a stroke at least six months ago and have difficulty walking. Success in this study means seeing improvements in walking tests like the 10-meter walk, Timed-Up-and-Go, and 6-minute walk tests after 12 weeks of exercise. The current status of this study is unclear.
- Study design
- This is an interventional study planning to enroll 55 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would participate in three weekly 25-60 minute cycling sessions for 12 weeks, for a total of 36 sessions. Your walking ability will be tested at the beginning and after 12 weeks of exercise.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your walking ability will be assessed at baseline (week 1) and after 12 weeks of exercise (week 14).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Biomarkers of Reaction To HIIT Exercise
At a glance
Conditions
NCT06059872
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Lisa C Krishnamurthy, PhD · PRINCIPAL_INVESTIGATOR · Atlanta VA Medical and Rehab Center, Decatur, GA
Who to contact
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Inclusion
Exclusion
What this trial measures
- 10 m walk test on a GAITRite matbaseline (week 1) and after the completion of 12 weeks of exercise (week 14)
To assess short-distance walking speed and gait characteristics.
- Timed-Up-and-Go (TUG) testbaseline (week 1) and after the completion of 12 weeks of exercise (week 14)
To assess short-distance walking and postural control.
- 6-minute walk testbaseline (week 1) and after the completion of 12 weeks of exercise (week 14)
To assess endurance.