LOTUS mHealth Intervention for HIV Prevention

This study is testing a mobile app called LOTUS to help people who use drugs engage more with HIV prevention services. The app offers tips, a community wall for support, reminders for HIV prevention, a way to ask healthcare professionals questions, and a resource database. We want to see if LOTUS is easy to use and helpful for people who use opioids and/or stimulants, are 18 or older, meet criteria for PrEP (Pre-Exposure Prophylaxis, a medicine to prevent HIV), and own a smartphone. The study will look at how many people use the app, how they like it, and if it helps them with HIV prevention over 6 months. The study is currently recruiting 40 women.

Study design
This is a single-arm study, meaning everyone receives the LOTUS intervention. It involves 40 participants and is not assigned a specific phase.
What's involved
Participants will use the LOTUS intervention for 6 months. Data will be collected at the start, at 3 months, and at 6 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months, with data collected at 3 and 6 months after starting the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06068283

An mHealth Intervention to Improve HIV Prevention Service Engagement Among People Who Use Drugs

Not Yet Recruiting
NAAges 18+InterventionalPrevention
University of California, San Diego
~40 participants
Updated 2026-06-26 on ClinicalTrials.gov
What's tested:LOTUS mHealth Intervention Group

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
LOTUS Feasibility
Measured over 6 months
+2 more outcomes measured
HIV Infections

NCT06068283

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of California San Diego

    La Jolla, Californiastudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

18 years of age or older
Report weekly or daily use of opioids and/or stimulants in the past 6 months
Meet current CDC eligibility criteria for PrEP
Report low levels of HIV prevention service engagement in the past 6 months
Not currently, or planning on becoming, pregnant during the study
Owns a smartphone with internet web-browsing capabilities

Exclusion

17 years of age or younger
Does not report weekly or daily use of opioids and/or stimulants in the past 6 months
Does not meet current CDC eligibility criteria for PrEP
Report high levels of HIV prevention service engagement in the past 6 months
Currently, or planning on becoming, pregnant during the study
Does not own a smartphone with internet web-browsing capabilities
  • LOTUS Feasibility6 months

    The feasibility of the LOTUS mHealth intervention will be measured by participant retention and via intervention use data.

  • LOTUS Acceptability6 months

    The acceptability of the LOTUS mHealth intervention will be measured via the System Usability Scale (SUS), with possible scores ranging from 10-50 and higher scores indicating higher acceptability.

  • HIV Prevention Service Engagement6 months

    The percentage of participants who report obtaining an HIV/STI test and/or initiating PrEP