Back to search results

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

This study is testing a treatment called stereotactic radiosurgery dorsal root rhizotomy (SRS) for spasticity (tight muscles) caused by stroke, spinal cord injury (SCI), or cerebral palsy. SRS uses precise radiation beams to target specific nerves in your back to help relax muscles. You could be in one of two groups: one receiving the SRS treatment, or a "sham" group receiving a fake treatment to ensure fair results. The study aims to see how much your muscle stiffness changes after 6 months. To join, you must be over 16, have chronic spasticity that hasn't responded to other treatments, and be able to lie still for the procedure.

Study design
This is an interventional study with 22 planned participants. Participants are randomly assigned to receive either the active treatment or a sham (fake) treatment.
What's involved
You would need to be able to lie flat on your back for the simulation and treatment. The study will assess changes in muscle stiffness 6 months after treatment.
Compensation
Not stated in the trial record.
Follow-up
Your muscle stiffness will be measured 6 months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06070233

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

Recruiting
NAAges 16+InterventionalTreatment
Ohio State University
~22 participants
Updated 2025-12-19 on ClinicalTrials.gov
What's tested:stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulationSham

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Modified Ashworth Scale
Measured over 6 months post treatment

Conditions

Spasticity as Sequela of Stroke
Spastic Cerebral Palsy
Spasticity, Muscle

Explore related trials

Spasticity

Where it's being run

2 sites across 2 states
Florida1
Ohio1

Study leadership

  • Joshua Palmer, MD · PRINCIPAL_INVESTIGATOR · Ohio State University

Who to contact

Uchechi Okafor, BS
[email protected]
(614) 2934876
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Chronic spasticity refractory to medical management or in a patient who cannot receive appropriate medical management mediated by one or more spinal nerve roots
Age \> 16 (if under 18, patients parents must sign consent).

Exclusion

Inability to lie supine for simulation \& treatment
Inability to visualize the target nerve on either CT or MRI imaging
Patients with confirmed pregnancy (all women of child-bearing age with intact uterus \& ovaries will be required to undergo a pregnancy test prior to simulation)

What this trial measures

  • Change in Modified Ashworth Scale6 months post treatment

    Change in the 6-month post-treatment Modified Ashworth Scale (MAS) measure of spasticity, which ranges from 0 (no symptoms) to 4 (worst symptoms)