ACHIEVE PATHFINDER: Portable Air Cleaners for Heart Failure
This study, called ACHIEVE PATHFINDER, is testing if portable air cleaners (PACs) can help people with heart failure (HF) after they leave the hospital. You would receive two PACs: either ones with special True HEPA filters or ones without filters (a control group). Researchers want to see if using these PACs for 90 days impacts your NTproBNP level, a marker for heart failure. You might be able to join if you are 18 or older, are currently in the emergency room or hospitalized for heart failure, or have a recent heart failure diagnosis with specific biomarker levels (BNP >200 ng/L or NTproBNP >1000 ng/L). The study is currently unclear on its recruitment status.
- Study design
- This is a randomized, blinded study involving 400 participants. Participants will be randomly assigned to receive PACs with filters or PACs without filters.
- What's involved
- Participants will use the assigned portable air cleaners for 90 days after hospital discharge. Your NTproBNP level will be measured at the start and after 90 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 90 days after hospital discharge to measure the impact of PAC use.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Project 4: ACHIEVE PATHFINDER
At a glance
Conditions
NCT06070428
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Henry Ford Health
Detroit, Michiganstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- David Lanfear, MD · PRINCIPAL_INVESTIGATOR · Henry Ford Health
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- The impact of PAC use for 90 days after hospital discharge for HF compared to sham on NTproBNP level.Baseline at hospital discharge to 90 days.
Change in NTproBNP from baseline to 90 days. This will be determined by comparing the NTproBNP value at the 90-day follow up visit versus the baseline NTproBNP value measured from blood draw at enrollment/randomization visit (within 48 hours of hospital discharge).