Dosing of Levothyroxine in Older Individuals with Hypothyroidism
This study is looking at how different doses of levothyroxine sodium, a common medicine for an underactive thyroid (hypothyroidism), affect older adults. You might be able to join if you are 65 or older, have had hypothyroidism for at least six months, and are already taking levothyroxine. The study aims to see if allowing more flexibility in levothyroxine dosing improves your quality of life related to your thyroid. We don't know the current recruitment status for this study.
- Study design
- This is a randomized, double-blind study involving 228 participants. It compares two different dosing strategies for levothyroxine over six months.
- What's involved
- You would be part of a study for six months, following a specific levothyroxine dosing strategy. The study will assess your symptoms, mood, sleep, memory, weight, lipids, and bone health.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome, Thyroid-Related Quality of Life, is measured at 6 months, which suggests the study duration for participants is at least this long.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Dosing of LT4 in Older Individuals
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Anne R. Cappola, M.D., Sc.M. · PRINCIPAL_INVESTIGATOR · University of Pennsylvania
Who to contact
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What this trial measures
- Thyroid-Related Quality of Life Patient-Reported Outcome Quality of Life scale6 months
22 items, scored 0-100, higher scores indicate worse status