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Almond Consumption and Skin Health Study

This study is looking into whether eating almonds can help improve skin health by affecting collagen, elastin, wrinkles, and skin discoloration (pigmentation). Researchers want to see if consuming 60 grams (about 2 ounces) of whole almonds five times a week can make a difference. They will compare this to a group eating a non-nut snack that has similar protein and calories. The study aims to measure changes in skin collagen and elastin levels, as well as facial wrinkles, after 24 weeks. Women between 35 and 70 years old, including both premenopausal and postmenopausal women, are eligible to participate. The study is currently unclear on its recruitment status and plans to enroll 60 participants.

Study design
This interventional study plans to enroll 60 women, aged 35-70, to compare the effects of eating almonds versus a non-nut snack.
What's involved
Participants will consume either 60 grams of whole almonds or a calorie-matched non-nut snack five times per week for 24 weeks.
Compensation
Not stated in the trial record.
Follow-up
Skin collagen, elastin, and facial wrinkles will be measured at 24 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06074276

The Effects of Almond on Facial Skin Collagen and Wrinkles

UNKNOWN
NAAges 35–70InterventionalTreatment
Integrative Skin Science and Research
~60 participants
Updated 2024-06-18 on ClinicalTrials.gov
What's tested:Food: whole almondsFood: non-nut snack

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Skin collagen and elastin quantification
Measured over 24 weeks
+1 more outcome measured

Conditions

Collagen Degeneration
Wrinkle
Pigmentation
Elastic Skin

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NCT06074276

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Integrative Skin Science and Research

    Sacramento, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Raja Sivamani, MD MS AP · PRINCIPAL_INVESTIGATOR · Integrative Skin Science and Research

Who to contact

Sarah Adnan
[email protected]
9168074299
Email the study team

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Eligibility criteria

Inclusion

Subjects 35 to 70 years of age of all skin types
50% of the subjects will be postmenopausal women determined as \>1-year loss of menstrual period
50% of the subjects will be premenopausal women
BMI 18.5 - 35 kg/m2
Individuals with a habitual diet that has been maintained for at least 6 months and to be maintained for the duration of the study
Individuals must maintain their usual skincare products, defined as products that has been used for at least 1 month, for the duration of the study

Exclusion

Those with a nut allergy
Those who are unwilling to discontinue oral collagen supplementation 1 month prior to the start of the study
Individuals who are unwilling to discontinue vitamin E or nut containing supplements 2 weeks prior to and during the intervention.
Individuals who are pregnant or breastfeeding
Change in skincare products during the study
Had a medical or cosmetic procedure such as laser resurfacing or plastic surgery to the face within the last 6 months (include botulinum toxin, dermal fillers, collagen, or other similar cosmetic procedure)
Has an autoimmune photosensitive condition or known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
Those with a skin disease on their face that would affect the assessment of their skin based on the assessment of the investigator.
Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years

What this trial measures

  • Skin collagen and elastin quantification24 weeks

    Assess with biopsy based histological examination

  • Facial wrinkles24 weeks

    Wrinkle severity score measured by Facial Image Analysis System (BTBP 3D image analysis system). Higher scores indicate worsened wrinkle severity and lower scores represent improvement in wrinkle severity.