Study on E-cigarettes vs. Nicotine Pouches for Smoking Cessation
This study is looking for 256 adults who currently smoke cigarettes and are willing to try switching to other products. It compares how effective e-cigarettes and nicotine pouches are at helping people reduce or stop smoking. You would be randomly assigned to use either an e-cigarette or a nicotine pouch for 4 weeks. The e-cigarettes come in different nicotine strengths (2.4% or 5%) and flavors (menthol and tobacco, or tobacco only). The nicotine pouches also come in different strengths (3mg or 6mg) and flavors (menthol and tobacco, or tobacco only). Researchers will measure how many cigarettes you smoke daily and how often you use the assigned product. To join, you must be at least 21 years old, speak English, and currently smoke cigarettes. You cannot be pregnant, breastfeeding, or using other smoking cessation medications. The study's current status is unclear.
- Study design
- This is an interventional study planning to enroll 256 participants. You would be randomly assigned to one of several groups testing different e-cigarette or nicotine pouch options.
- What's involved
- You would have an intake visit lasting about 60 minutes, followed by four bi-weekly visits (in person or by video call) lasting about 30 minutes each, over a total of 6 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your cigarette smoking and product use will be measured from the start of the study until week 4.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Lisa Fucito, PhD · PRINCIPAL_INVESTIGATOR · Yale University
- Krysten Bold, PhD · PRINCIPAL_INVESTIGATOR · Yale University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Aim 1: Average number of cigarettes smoked per dayFrom baseline to week 4
Participants will report the total number of cigarettes consumed each day using a well-validated timeline follow-back (TLFB) interview method to assess number of cigarettes smoked per day continuously over the 4-week observational period for each product condition.
- Aim 2: Percent of days using non-combustible productFrom baseline to week 4
Participants will report daily use of e-cigarettes or nicotine pouches using a well-validated timeline follow-back (TLFB) interview method continuously over the 4-week observational period to determine the total percent days use of the non-combustible product for each product condition.