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NCT06077422

Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain

Enrolling by Invitation
PHASE2Ages 18+InterventionalTreatment
Rutgers, The State University of New Jersey
~150 participants
Updated 2026-02-17 on ClinicalTrials.gov
What's tested:bupivacaine liposome injectable suspensionBupivacaine Hydrochloride

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Postoperative opioid consumption
Measured over Postoperative days 0 through 5

Conditions

Pain, Postoperative
Opioid Use
Perioperative Complication
Heart Diseases

Explore related trials

Heart DisorderPost-Operative Pain

Where it's being run

1 sites across 1 states
New Jersey1

Study leadership

  • Leonard Y Lee, MD · PRINCIPAL_INVESTIGATOR · Rutgers Robert Wood Johnson Medical School, Dept of Surgery

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults (18 years-no upper age limit)
Scheduled for mini thoracotomy (i.e. valve repair) or open sternotomy (i.e. bypass graft) at single academic medical center (in and out-patients).

Exclusion

Are currently on pain medication or pain regimen for chronic pain condition
Convert to sternotomy (for thoracotomies)
Require, upon intraoperative discovery and surgeon's decision, the need for an unplanned secondary procedure other than the originally scheduled index operation
Undergo emergent surgery
Are non-English speaking (The majority of the PI's patient population speak English. As a pilot study the investigators cannot afford to enroll non-English speaking subjects due to time, personnel, and financial constraints.)
Mechanical circulatory support (MCS)
Vasoactive medications
Intubated
Active infection
Patients otherwise deemed ineligible for ESP block by the investigators due to safety concerns.

What this trial measures

  • Postoperative opioid consumptionPostoperative days 0 through 5

    Postoperative opioid consumption within first five postoperative days, reported as average mg/day in morphine equivalents.