This study is looking for people with and without Huntington Disease (HD) to help researchers discover new ways to track the disease. The main goal is to find a blood-based biomarker (a measurable indicator) of the Huntingtin (HTT) protein, which is involved in HD, using tiny particles called extracellular vesicles (EVs). EVs are naturally released from cells in the brain and can be found in blood. This biomarker could then be used in future clinical trials to see how well new treatments are working. You can join if you are between 18 and 75 years old, can give informed consent, speak English, and are willing to follow study procedures like blood collection and a lumbar puncture (spinal tap). The study aims to enroll 100 participants.

Study design

This is an observational study, meaning participants are monitored without receiving a specific intervention. It aims to enroll 100 participants.

What's involved

You would need to comply with study procedures, including overnight fasting, blood collection, and a lumbar puncture (spinal tap). The duration of these commitments is not specified, but the primary endpoint is measured at 1 year.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured at 1 year, suggesting participants will be followed for at least that long.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.