Comparing Pain Blocks After DIEP Surgery

This study is comparing two different pain-relief procedures for women undergoing DIEP flap surgery (a type of breast reconstruction after mastectomy). Researchers want to see if Erector Spinae Plane blocks (ESPBs) are as good as or better than Transversus Abdominus Plane blocks (TAPs) at controlling pain. Both procedures involve injecting a local anesthetic like ropivacaine to numb the area. You could be eligible if you are an adult woman (18-70 years old) with breast cancer, generally healthy (ASA 1-3), and are having DIEP flap surgery. The study will measure your pain levels and how much pain medication you need 24 hours after the injection to see which method is more effective. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 102 participants. Participants will be randomly assigned to receive either an Erector Spinae Plane block or a Transversus Abdominus Plane block.
What's involved
Participants will receive their assigned block either before surgery (ESPBs) or on the morning of surgery (TAPs). Pain levels and pain medication use will be measured 24 hours after the injection.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 hours after the injection to measure pain and medication use.

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NCT06091241

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Recruiting
NAAges 18–70InterventionalPrevention
University of Kansas Medical Center
~102 participants
Updated 2026-06-04 on ClinicalTrials.gov
What's tested:Pre-operative Erector Spinae Plane block prior to DIEP surgeryPre-operative Transversus Abdominus Plane blocks prior to DIEP surgery

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Numerical Rating Scale
Measured over 24 hours post injection
+1 more outcome measured
Pain
1 sites across 1 states
Kansas1

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Eligibility criteria

Inclusion

Adult women with breast cancer, ASA 1-3, undergoing DIEP flap surgery

Exclusion

Chronic opioid use contraindications to local anesthetics or regional analgesia Inability to communicate intensity of pain on a numeric analog scale
  • Numerical Rating Scale24 hours post injection

    Scale used to measure pain on scale from 0-10 (0 is 'no pain' and 10 is 'the worst pain imaginable')

  • Mean Morphine Equivalents24 hours post injection

    Amount of opioid pain medications administered and converted to morphine equivalents