tACS to Enhance Language Abilities in Stroke-Related Aphasia

This study is looking at whether transcranial alternating current stimulation (tACS) can improve language skills in people who have aphasia (difficulty with language) after a stroke. tACS is a device that sends a low-level electrical current to the brain through patches on the scalp. Participants will receive both active tACS and a sham (fake) tACS. Researchers will compare language test results after these sessions to see if tACS helps. They are also comparing people with aphasia to healthy individuals to understand how brain responses to tACS might differ. The study aims to enroll 120 participants, including those aged 18 to 85 who have chronic aphasia from a single left-sided stroke, and healthy right-handed controls. The study's status is currently unclear.

Study design
This is an interventional study planning to enroll 120 participants. It compares active transcranial alternating current stimulation (tACS) with sham (fake) tACS.
What's involved
Participants will receive single sessions of active and sham tACS. Language abilities will be measured 5-10 minutes after each session.
Compensation
Not stated in the trial record.
Follow-up
Language abilities are measured 5-10 minutes after a single session of tACS.

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NCT06092814

tACS to Enhance Language Abilities

Recruiting
NAAges 18–85InterventionalTreatment
University of Pennsylvania
~120 participants
Updated 2026-08-24 on ClinicalTrials.gov
What's tested:Active transcranial alternating current stimulation (tACS)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Performance on the Blocked-Cyclic Naming (BCN) Task
Measured over 5-10 minutes after a single session of active (alpha tACS) and sham (fake tACS).
Stroke
Aphasia, Acquired
Aphasia

NCT06092814

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Pennsylvania

    Philadelphia, Pennsylvaniastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • Performance on the Blocked-Cyclic Naming (BCN) Task5-10 minutes after a single session of active (alpha tACS) and sham (fake tACS).

    The BCN tasks involves naming a set of pictures repeatedly. Sets of pictures come from either the same semantic category (high competition condition; e.g., categorically related: "dog", "cat", "panda") or different semantic categories (low competition condition; e.g., unrelated: dog, eye, crib).